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PREPARE

Africa Pandemic sciences, banner. TGHN
  • CLEAR-Africa
  • Harnessing mosquitoes for epidemic … rch in Africa
  • ACCEPT-Africa
  • Strengthening Clinical and Genomics … Arboviruses
  • SHARPER
  • PREPARE
  • SPIL-OVA

PREPARE

 

Prevention and Response to Emerging viruses with Pandemic potential in Africa (PREPARE)


Research area
Vaccinology / Early stage vaccine research

Lead Institution
African Population and Health Research Center (Dr Florah Karimi)

Partners

  • Centre Hospitalier Universitaire Bouaké,
  • Université Alassane Ouattara, Bouaké, Côte d’Ivoire (Professor Chantal Akoua-Koffi),
  • Institut National de Recherche Biomedicale, Democratic Republic of the Congo (Professor Placide Mbala),
  • Kenya Medical Research Institute (Professor Kariuki Njenga), Uganda Virus Research Institute (Dr Bakamutumaho Barnabas ),
  • Wits Health Consortium, South Africa (Professor Marietjie Venter )

Project
Prevention and Response to Emerging viruses with Pandemic potential in Africa (PREPARE)


This project will enhance Africa’s capacity to combat emerging and reemerging pathogens by establishing key nodes across South, East, and West Africa focused on clinical disease surveillance, diagnostic and genomic capacity, and vaccine development. This is in recognition of the fact that robust One Health research networks are essential for the early detection, prevention, and control of epidemic-prone vector-borne, zoonotic and respiratory viruses.

Through this programme, clinical sites in South Africa, Uganda, Kenya, the Democratic Republic of the Congo and Côte d'Ivoire will use both retrospectively-collected samples and expanded prospective syndromic surveillance in humans, animals and the environment to detect both known and unknown pathogens and to implement multi-pathogen molecular, serological and rapid diagnostics. Capacity strengthening is a cornerstone of this programme and enhances local capacity to respond effectively during evolving epidemics and pandemics while also fostering sustainable and resilient research networks for epidemic preparedness throughout Africa.

This comprehensive approach facilitates the rapid development of strategies and products aimed to minimize the impact of emerging pathogens.

Prevention and Response to Emerging viruses with Pandemic potential in Africa (PREPARE)


Domaine de recherche
Vaccinology / Early stage vaccine research

Institution chef de file
African Population and Health Research Center (Dr Florah Karimi)

Partenaires

  • Centre Hospitalier Universitaire Bouaké,
  • Université Alassane Ouattara, Bouaké, Côte d’Ivoire (Professor Chantal Akoua-Koffi),
  • Institut National de Recherche Biomedicale, Democratic Republic of the Congo (Professor Placide Mbala),
  • Kenya Medical Research Institute (Professor Kariuki Njenga), Uganda Virus Research Institute (Dr Bakamutumaho Barnabas ),
  • Wits Health Consortium, South Africa (Professor Marietjie Venter )

Projet
Prevention and Response to Emerging viruses with Pandemic potential in Africa (PREPARE)


Ce projet renforcera la capacité de l’Afrique à lutter contre les agents pathogènes émergents et réémergents en établissant des pôles clés en Afrique australe, orientale et occidentale, axés sur la surveillance clinique des maladies, les capacités diagnostiques et génomiques, ainsi que le développement de vaccins. Cette approche reconnaît que des réseaux de recherche solides fondés sur le concept « Une seule santé » sont essentiels pour la détection précoce, la prévention et le contrôle des virus à transmission vectorielle, zoonotique et respiratoire à potentiel épidémique.

Dans le cadre de ce programme, des sites cliniques en Afrique du Sud, en Ouganda, au Kenya, en République démocratique du Congo et en Côte d’Ivoire utiliseront à la fois des échantillons collectés rétrospectivement et une surveillance syndromique prospective élargie chez les humains, les animaux et dans l’environnement afin de détecter des agents pathogènes connus et inconnus, et de mettre en œuvre des diagnostics moléculaires, sérologiques et rapides multipathogènes. Le renforcement des capacités constitue un pilier central de ce programme, améliorant les capacités locales à répondre efficacement lors d’épidémies et de pandémies en évolution, tout en favorisant des réseaux de recherche durables et résilients pour la préparation aux épidémies à travers l’Afrique.

Cette approche globale facilite le développement rapide de stratégies et de produits visant à minimiser l’impact des agents pathogènes émergents.

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